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Your doctor may arrange investigations including a full blood count, serum folate levels, and in some cases, anti-intrinsic factor antibodies if pernicious anaemia hasn't been previously confirmed
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Among approaches to counteract ADO-mediated immunosuppression ( Supplementary Table 1 ), ADA-based degradation (97, 102) is currently the most feasible, given the complexity of receptor-specific blockade (103), the limited potency of small-molecule CD38 inhibitors (104), and the presence of alternative ADO-generating pathways (105)
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