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SGK‐1 is phosphorylated at Ser422 in its hydrophobic region by mTORC2 (Luo et al., 2018) and functions as an effector modulated by the insulin/IGF‐1 pathway, involved in the stress response through the negative regulation of the skinhead 1 (skn‐1)/nuclear factor erythroid 2‐related factor 2 (NRF2) pathway (Aspernig et al., 2019
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