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AAPC Chapter 4 Questions & Answers -Fully Solved | Exams Advanced Education | Docsity
To establish whether NRF2 is the mediator of exhaustion in the context of KEAP1 deficiency, we genetically ablated NRF2 in KEAP1-deficient CD8 + T cells using CRISPR–Cas9 gene editing (Supplementary Table 2) 27
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