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Cecal samples Cecal weight was measured since the weight of this portion of the intestine appears to be highly influenced by the microbiome (e.g., certain antibiotic treatments dramatically increase cecal weight 27,28,29,30,31 but not the colon 27 )

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For example, drug development targeting the repair of intestinal barrier function can promote the proliferation and differentiation of intestinal epithelial cells and increase the expression of intercellular tight junction proteins to fundamentally improve intestinal barrier function and reduce the occurrence of inflammation