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Other FAD-containing ubiquinone-reducing enzymes which feed electrons into the ETC include succinate dehydrogenase in Complex II, the electron transport flavoprotein-ubiquinone oxidoreductase (ETF dehydrogenase) and mitochondrial glycerol-3-phosphate dehydrogenase (118–120)
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Subsequent studies have further elucidated the molecular mechanisms through which NRF2 modulates ferroptosis, revealing its involvement across multiple ferroptotic axes, including iron homeostasis, GSH metabolism and lipid metabolism [30] (Fig
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