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Mechanisms regulating intestinal barrier integrity and its pathological implications | Experimental & Molecular Medicine
Some of the primary genes impacted are COL1A1 (matrix), VEGFA (angiogenesis), IL6 (inflammation), and SOD2 (oxidative defense)
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FXS results from loss of function of the fragile X mental retardation 1 ( FMR1 ) gene, which encodes the fragile X mental retardation protein (FMRP), a RNA-binding protein important for the regulation of local dendritic protein translation (Bagni and Greenough 2005
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