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The connection between lower level of GSH and the dysregulation of leukocyte-associated cytokines in HIV-positive plasma samples was also established, suggesting a correlation between inflammatory state and GSH level, and subsequent decrease in the levels of free radicals and immunosuppressive cytokines followed supplementing subjects with L-GSH [39]

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R min and R max were obtained by fitting the R values and the lysate-based GSH concentrations C GSH using equation: ( R − R min )/( R max − R )= k × C GSH , in which k is a constant