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Blocking one-carbon metabolism promotes ROS accumulation leading to cell proliferation arrest Given that one-carbon metabolism controls redox balance, which protects cancer cells from growth arrest during diverse stresses [23, 37,38,39], we next studied one-carbon metabolism and its causal relationship with resistance to glutamine metabolism inhibition
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Curcumin, known as a potent PPAR γ agonist, protected neurons and suppressed neuroinflammatory responses in a rat stroke model (Liu et al., 2013c)
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