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Structure and chemistry Human IGF-1 is a 70-residue single-chain polypeptide of about 7.6 kDa with B, C, A and D domains, homologous to proinsulin, and held together by three disulfide bonds (Cys6-Cys48, Cys18-Cys61 and Cys47-Cys52)
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These findings were further confirmed by the CCK-8 viability assay
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